• intloko_ibhena_01

I-PLA porous microneedles: ukufunyanwa ngokukhawuleza kwe-covid-19 antibody ngaphandle kweesampuli zegazi

Abaphandi baseJapan baphuhlise indlela entsha esekwe kwi-antibody yokufunyaniswa ngokukhawuleza nangokuthembekileyo kwenoveli coronavirus ngaphandle kwemfuneko yeesampulu zegazi. Iziphumo zophando zipapashwe kutshanje kwingxelo yeSayensi yeSayensi.
Ukuchongwa okungasebenziyo kwabantu abosulelwe yi-covid-19 kunciphise kakhulu impendulo yehlabathi kwi-COVID-19, eyongezwa lizinga eliphezulu losulelo lwe-asymptomatic (16% - 38%). Ukuza kuthi ga ngoku, eyona ndlela yokuvavanya kukuqokelela iisampuli ngokusula impumlo nomqala. Nangona kunjalo, ukusetyenziswa kwale ndlela kunqunyelwe ixesha elide lokufumanisa (iiyure ze-4-6), iindleko eziphezulu kunye neemfuno zezixhobo zobugcisa kunye nabasebenzi bezonyango, ngakumbi kumazwe anezibonelelo ezilinganiselweyo.
Emva kokuqinisekisa ukuba i-interstitial fluid inokulungela ukubhaqwa kwe-antibody, abaphandi baphuhlise indlela entsha yokuthatha isampulu kunye novavanyo. Okokuqala, abaphandi baphuhlise i-biodegradable porous microneedles eyenziwe nge-polylactic acid, enokuthi ikhuphe i-interstitial fluid eluswini lomntu. Emva koko, baye benza i-immunoassay biosensor esekwe ephepheni ukuze bafumane ii-antibodies ezithile ze-covid-19. Ngokudibanisa ezi zinto zimbini, abaphandi benza i-compact patch ekwazi ukubona i-antibodies kwisayithi kwimizuzu ye-3.


Ixesha lokuposa: Jul-06-2022